conclusions our study showed that the prevalence of esbl-producing k. pneumoniae at king khalid hospital was significantly high. routine detection of esbl-producing microorganisms is required by each of the laboratory standard detection methods to control the spread of these infections and allow a proper therapeutic strategy. for detection, the phenotypic confirmatory disc diffusion test is sim...

background extended-spectrum β-lactamase (esbl) production is the major resistance mechanism to β-lactam antibiotics in enterobacteriaceae. in addition, emergence of plasmid-mediated quinolone resistance (pmqr) in esbl-producing isolates has become a global threat for treatment of these infections. objectives we investigated the association between esbl production and quinolone resistance in ur...

listeria monocytogenes can cause serious infection and recently, relapse of listeriosis has been reported in leukemia and colorectal cancer, and the patients with klebsiella pneumoniae are at increased risk of colorectal cancer. translation initiation codon recognition is basically mediated by shine-dalgarno (sd) and the anti-sd sequences at the small ribosomal rna (ssu rrna). in this research,...

the objective of this study was to determine the phenotypic characteristics of kpc-producing pseudomonas aeruginosa and acinetobacter baumannii isolates. a case report study was performed at a tertiary burn care centre in tehran,  iran.  nine  isolates  of pseudomonas  aeruginosa  and  acinetobacter baumannii from a hospitalized case were isolated. the identity of isolates was confirmed and the...

Listeria monocytogenes can cause serious infection and recently, relapse of listeriosis has been reported in leukemia and colorectal cancer, and the patients with Klebsiella pneumoniae are at increased risk of colorectal cancer. Translation initiation codon recognition is basically mediated by Shine-Dalgarno (SD) and the anti-SD sequences at the small ribosomal RNA (ssu rRNA). In this research,...

background: klebseilla pneumoniae causes urinary tract infections, nosocomial pneumonia and intra-abdominal infections. capsular antigens are considered to be the ultimate virulence determinants. among 77 capsular serotypes of k. pneumoniae, serotypes k1 and k2 are the most virulent ones in humans. objectives: we designed a pcr method for detection of capsular serotypes k1 and k2 of k. pneumoni...

background: the increasing pattern of multi-drug resistant (mdr) bacteria has limited therapeutic options especially for nosocomial isolates of klebsiella pneumoniae. therefore, the aim of this study was the molecular detection of 16s rrna methylase and blactx-m-15 among k. pneumoniae strains isolated from hospitalized patients in mofid, imam hossein and taleghani hospitals. materials and metho...

b ackground: in recent decades, extended spectrum beta-lactamase (esbl) producing bacteria have increased worldwide. the most important causative agents of nosocomial infections throughout the world, escherichia coli and klebsiella pneumoniae as main esbl-producing bacteria are so highly regarded. trends  in  the  treatment  of  infections  by such  bacteria  have  led  to  a  global concern. t...

Overuse and misuse of antibiotics leads to rapid evolution of antibiotic-resistant bacteria and antibiotic resistance genes. Klebsiella pneumoniae has become the most common pathogenic bacterium accountable for nosocomial infections due to its high virulence factor and general occurrence of resistance to most antibiotics. The β-lactamase signaling pathway has been suggested to be involved in an...